Diuretic Strategies in Patients with Acute Decompensated Heart Failure | NEJM
How to design a dose-finding study using the continual reassessment method | BMC Medical Research Methodology | Full Text
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers | BMC Pulmonary
The future of drug development: advancing clinical trial design | Nature Reviews Drug Discovery
Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial - ScienceDirect
Diuretic Strategies in Patients with Acute Decompensated Heart Failure | NEJM
Phase 2 randomized dose-finding sham-controlled trial in New York Heart... | Download Scientific Diagram
Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer
Diuretic Strategies in Patients with Acute Decompensated Heart Failure - ppt download
Clinical and Pharmacological Effects of Apixaban Dose Adjustment in the ARISTOTLE Trial | Journal of the American College of Cardiology
DESTINY-Lung02 Trial | ENHERTU® (fam-trastuzumab deruxtecan-nxki)
Efficacy and Safety of Sacubitril/Valsartan by Dose Level Achieved in the PIONEER-HF Trial | JACC: Heart Failure
First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers: Molecular Therapy - Nucleic Acids
Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial - eClinicalMedicine
Trial Design Including Dose Escalation and Treatment Schedule 2a)... | Download Scientific Diagram
UK launches booster dose trial of seven Covid-19 vaccines
Schema of the ARREST clinical trial. The initial dose level will be... | Download Scientific Diagram
 "Johnson & Johnson Starts Two-Dose Trial Of Its Covid Candidate Vaccine In UK")
Johnson & Johnson Starts Two-Dose Trial Of Its Covid Candidate Vaccine In UK
On Biostatistics and Clinical Trials: Phase I Dose Escalation Study Design: "3 + 3 Design"
Trial design and dosing schema. (a) The trial replicates patients' last... | Download Scientific Diagram
How a COVID-19 vaccine trial error led to an unexpected discovery
Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial - The Lancet
Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial - The Lancet
A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis - ScienceDirect
Dose escalation design for the Part 1 of the trial. Single patients... | Download Scientific Diagram
