Phase I/II study of oxaliplatin dose escalation via a laparoscopic approach using pressurized aerosol intraperitoneal chemotherapy (PIPOX trial) for nonresectable peritoneal metastases of digestive cancers (stomach, small bowel and colorectal ...
Immune checkpoint inhibitor-based combinations: is dose escalation mandatory for phase I trials? - Annals of Oncology
Phase 1 clinical trials: Designs and considerations
Cancers | Free Full-Text | Phase 1 Dose Escalation Study of the Allosteric AKT Inhibitor BAY 1125976 in Advanced Solid Cancer—Lack of Association between Activating AKT Mutation and AKT Inhibition-Derived Efficacy
Dose-finding trials: why not to use algorithmic designs
A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody to IL-6 in CKD | American Society of Nephrology
Moving Beyond 3+3: The Future of Clinical Trial Design | American Society of Clinical Oncology Educational Book
Contemporary dose-escalation methods for early phase studies in the immunotherapeutics era - ScienceDirect
The Classic 3 + 3 Design in Dose-finding Clinical Trials and Its Alternatives | Genpro Research
JCI Insight - First-in-human trial of multikinase VEGF inhibitor regorafenib and anti-EGFR antibody cetuximab in advanced cancer patients
The 3 + 3 dose escalation study design. DLT, dose limiting toxicity;... | Download Scientific Diagram
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study | Semantic Scholar
The Expansion Phase of Phase I Oncology Trials
Flexibility of the BLRM in Dose-Escalation Trials
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial - The Lancet
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PDF] Dose Escalation Methods in Phase I Cancer Clinical Trials | Semantic Scholar
Dose escalation. The dose escalation was performed in both intra and... | Download Scientific Diagram
Innovative design for a phase 1 trial with intra-patient dose escalation: The Crotoxin study - ScienceDirect
توییتر \ Stephen V Liu, MD در توییتر: «#OncoAlert #AACR20 Dose escalation of TAK-788 (mobocertinib) established MTD of 160mg qday. DLTs were 1 case each of grade 3 diarrhea, grade 3 mucositis,
Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46) - eBioMedicine
A new pragmatic design for dose escalation in phase 1 clinical trials using an adaptive continual reassessment method | BMC Cancer | Full Text
Dose escalation and expansion (phase Ia/Ib) study of GLS-010, a recombinant fully human antiprogrammed death-1 monoclonal antibody for advanced solid tumors or lymphoma - European Journal of Cancer
On Biostatistics and Clinical Trials: Phase I Dose Escalation Study Design: "3 + 3 Design"
Inter-patient and intra-patient dose escalation strategy. Patients were... | Download Scientific Diagram
Dose Escalation and Co-therapy Intensification Between Etanercept, Adalimumab, and Infliximab: The CADURA Study
